Early years of life: how crucial for long-term health? - Microbiota events
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Early years of life: how crucial for long-term health?

It is established that the 1000 first days of life are an important window for later health. The establishment of the gut microbiota is included in this time window:  its formation starts during the birthing process when the neonate is suddenly immersed in a varied bacterial environment. This initial microbiota constitutes a dynamic and delicate ecosystem that gradually shapes itself and shifts toward an adult-like configuration around 2-3 years.

 

Various perinatal determinants, such as cesarean section delivery, type of feeding, gestational age, environment, and antibiotic treatments may affect the pattern of bacterial colonization and result in an imbalance in the composition and function of microbiota. This phenomenon is called dysbiosis.

 

Antibiotics have saved millions of lives, but their overuse or misuse is one of the main causes of dysbiosis. Antibiotic exposure during the first years of life, is associated with increased risk of short-term consequences, such as diarrhea. It is also associated with risk of diseases which may appear later in life, including obesity, types 1 and 2 diabetes, inflammatory bowel diseases, celiac disease, allergies, and asthma. That is why it is important to protect infant and child’s microbiota. Prescribing some specific strains probiotics is a way to protect microbiota like Saccharomyces boulardii CNCM I-745. Indeed, this yeast probiotic can play a key role in protecting and restoring infant or child’s microbiota when is prescribed with antibiotic treatment.

 

Early years of life: how crucial for long-term health?

It is established that the 1000 first days of life are an important window for later health. The establishment of the gut microbiota is included in this time window:  its formation starts during the birthing process when the neonate is suddenly immersed in a varied bacterial environment. This initial microbiota constitutes a dynamic and delicate ecosystem that gradually shapes itself and shifts toward an adult-like configuration around 2-3 years.

 

Various perinatal determinants, such as cesarean section delivery, type of feeding, gestational age, environment, and antibiotic treatments may affect the pattern of bacterial colonization and result in an imbalance in the composition and function of microbiota. This phenomenon is called dysbiosis.

 

Antibiotics have saved millions of lives, but their overuse or misuse is one of the main causes of dysbiosis. Antibiotic exposure during the first years of life, is associated with increased risk of short-term consequences, such as diarrhea. It is also associated with risk of diseases which may appear later in life, including obesity, types 1 and 2 diabetes, inflammatory bowel diseases, celiac disease, allergies, and asthma. That is why it is important to protect infant and child’s microbiota. Prescribing some specific strains probiotics is a way to protect microbiota like Saccharomyces boulardii CNCM I-745. Indeed, this yeast probiotic can play a key role in protecting and restoring infant or child’s microbiota when is prescribed with antibiotic treatment.

 

Program

This virtual event focuses on providing key information on how microbiota settles itself in the gut of children and the possible harmful effects of antibiotics on it.

 

In a dynamic and interactive way, this TV show is hosted by a scientific journalist, Sue Saville, who will interview Prof. Marie Claire Arrieta and Prof. Ener Cagri Dinleyici. They will discuss about how our early days set the tone for the quality of life later, and how our dynamic gut ecosystem gradually shaping itself.

 

They will also talk about the factors that can alter the children microbiota and why it is important to take care of it, especially in context of antibiotics treatment. Indeed, there are short and long-term impact of the antibiotic therapy but probiotics such as Saccharomyces boulardii CNCM I-745 can play a key role protecting microbiota children when prescribing antibiotics.

About the speakers

Dr. Marie-Claire Arrieta

Assistant Professor in the departments of Physiology, Pharmacology and Pediatrics of the University of Calgary, (Calgary, Canada).

Dr. Marie-Claire Arrieta is an Assistant Professor in the departments of Physiology, Pharmacology and Pediatrics of the University of Calgary. Her research group explores the intestinal colonization with microbes early in lab, its ecological patterns, and immune consequences to humans.

Prof. Ener Cagri Dinleyici

Professor of Pediatrics at the Eskisehir Osmangazi University Faculty of Medicine, (Eskisehir, Turkey).

Ener Cagri Dinleyici is Professor of Pediatrics at the Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey. His work focuses on microbiota, pediatric vaccine, pediatric infectious disease, pediatric intensive care. He is vice-president of the World Scientific Association of Probiotics Prebiotics in Pediatrics and member of numerous scientific societies.

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