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Create a free account or log inVulnerability of the gut microbiota in industrialized societies
Diet and medications are the main drivers of the composition and functional diversity of the human microbiome. Medications such as antibiotics have saved millions of lives, but their over prescription have led to the emergence of resistant infections and has harmful effects on the microbiome. Gut microbes can also influence the efficacy of medications. The knowledge of the bidirectional interactions between some drugs and the gut microbiome can aid practitioners in determining which interventions modulate interactions and optimize treatment efficacy.
Vulnerability of the gut microbiota in industrialized societies
Diet and medications are the main drivers of the composition and functional diversity of the human microbiome. Medications such as antibiotics have saved millions of lives, but their over prescription have led to the emergence of resistant infections and has harmful effects on the microbiome. Gut microbes can also influence the efficacy of medications. The knowledge of the bidirectional interactions between some drugs and the gut microbiome can aid practitioners in determining which interventions modulate interactions and optimize treatment efficacy.
Program
This 90 minutes Biocodex/Zambon webinar focuses on the bidirectional interactions between some commonly used drugs and the gut microbiome.
After a brief introduction by Prof. Henry Cohen (Chairman), Prof. Miguel Valdovinos develops the mechanisms by which some medications like proton-pump inhibitors and antidiabetic drugs alter the composition and function of the gut microbiota. He also discusses the potential impact of microbiota on the efficacy of drugs and the future of pharmacomicrobiomics (25’ talk).
Then, Prof. Guarner’s talk (25’) follows with a focus on antibiotics and their role as disruptors of the diversity and richness of gut microbiota (dysbiosis). He also describes the potential role of diet and probiotics as a natural and effective way to improve diversity and prevent gut dysbiosis.
The webinar ends with a Q/A session moderated by Prof. Cohen.
About the speakers
Prof. Francisco Guarner
Consultant of gastroenterology, Centro Médico Teknon (Barcelona, Spain)
Prof. Francisco Guarner is Consultant of Gastroenterology at the University Hospital Vall d’Hebron and Senior Researcher at the Digestive System Research Unit at the Vall d’Hebron Research Institute in Barcelona, Spain. Prof. Guarner also serves as a member of the ‘Guidelines & Publications Committee’ of the World Gastroenterology Organization (WGO), Chair of the Steering Committee of the International Human Microbiome Consortium and member of the Scientific Committee of Gut Microbiota for Health Section of the European Society of Neurogastroenterology & Motility.
Prof. Miguel Ángel Valdovinos Díaz
Professor and laboratory head of gastroenterology and gastrointestinal motility, National Autonomous University of Mexico (Mexico City, Mexico)
Prof. Miguel A. Valdovinos is the Head of the Neurogastroenterology and Motility Unit at “Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán" (Mexico City, Mexico). He is also a Professor of Gastroenterology and Gastrointestinal Motility at the National Autonomous University of Mexico; a public research University considered the largest University in Latin America and has one of the biggest campuses in the world. Prof Valdovinos is the Director of Training Center of the City of Mexico for the World Gastroenterology Organization.
Prof. Henry Cohen
Professor and chairman of gastroenterology, Hospital de Clínicas (Montevideo, Uruguay)
Prof. Henry Cohen is a Professor and Chairman of Gastroenterology at Hospital de Clínicas (National University of Uruguay). He is also the Director of ECHO (Extension for Community Healthcare Outcomes) Project Uruguay. ECHO is an international collaborative model of medical education and care management that helps clinicians provide expert-level care to patients wherever they live. Prof. Cohen is former President and Master of the World Gastroenterology Organization (WGO).
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